node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
M231_00276 | M231_01309 | A0A4Q1BW56 | A0A4Q1BTK0 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | 0.961 |
M231_00276 | M231_04267 | A0A4Q1BW56 | A0A4Q1BL36 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.916 |
M231_00276 | M231_05002 | A0A4Q1BW56 | A0A4Q1BJ71 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.865 |
M231_00276 | M231_05009 | A0A4Q1BW56 | A0A4Q1BJC9 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 2-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase). | 0.992 |
M231_00276 | M231_05137 | A0A4Q1BW56 | A0A4Q1BIY4 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Dihydrolipoyl dehydrogenase. | 0.907 |
M231_00276 | M231_05799 | A0A4Q1BW56 | A0A4Q1BH92 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Uncharacterized protein. | 0.890 |
M231_00276 | M231_05882 | A0A4Q1BW56 | A0A4Q1BGZ8 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.977 |
M231_00276 | M231_06124 | A0A4Q1BW56 | A0A4Q1BGH2 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.998 |
M231_00276 | M231_07548 | A0A4Q1BW56 | A0A4Q1BAV9 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Glutaryl-CoA dehydrogenase. | 0.405 |
M231_00276 | M231_07865 | A0A4Q1BW56 | A0A4Q1BB12 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.862 |
M231_01309 | M231_00276 | A0A4Q1BTK0 | A0A4Q1BW56 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.961 |
M231_01309 | M231_04267 | A0A4Q1BTK0 | A0A4Q1BL36 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.902 |
M231_01309 | M231_05002 | A0A4Q1BTK0 | A0A4Q1BJ71 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.920 |
M231_01309 | M231_05009 | A0A4Q1BTK0 | A0A4Q1BJC9 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | 2-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase). | 0.998 |
M231_01309 | M231_05137 | A0A4Q1BTK0 | A0A4Q1BIY4 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Dihydrolipoyl dehydrogenase. | 0.993 |
M231_01309 | M231_05799 | A0A4Q1BTK0 | A0A4Q1BH92 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Uncharacterized protein. | 0.914 |
M231_01309 | M231_05882 | A0A4Q1BTK0 | A0A4Q1BGZ8 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.916 |
M231_01309 | M231_06124 | A0A4Q1BTK0 | A0A4Q1BGH2 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.885 |
M231_01309 | M231_07548 | A0A4Q1BTK0 | A0A4Q1BAV9 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Glutaryl-CoA dehydrogenase. | 0.921 |
M231_01309 | M231_07865 | A0A4Q1BTK0 | A0A4Q1BB12 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.881 |