STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M231_00948Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (969 aa)    
Predicted Functional Partners:
M231_03901
DNA repair protein rad18.
    
 0.994
M231_06198
E3 ubiquitin protein ligase.
    
 0.993
M231_02548
Ubiquitin-activating enzyme E1.
   
 0.982
M231_07228
Polyubiquitin.
   
 0.968
M231_01603
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 
 0.956
M231_05948
HECT domain-containing protein.
    
 0.922
M231_03340
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.902
M231_05107
Ubiquitin-40S ribosomal protein S27a.
   
 0.895
M231_00003
CIA30 domain-containing protein.
   
 0.895
M231_03897
Ubiquitin-like domain-containing protein.
   
 0.856
Your Current Organism:
Tremella mesenterica
NCBI taxonomy Id: 5217
Other names: CBS 6973, T. mesenterica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.