STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV37450.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: dar:Daro_0672 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (318 aa)    
Predicted Functional Partners:
ACV35367.1
Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: lch:Lcho_3177 hydroxypyruvate reductase.
 
 0.954
ACV37100.1
KEGG: azo:azo1159 malate synthase; TIGRFAM: malate synthase A; PFAM: malate synthase; Belongs to the malate synthase family.
  
 
 0.927
ACV35921.1
2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: dar:Daro_3339 6-phosphogluconate dehydrogenase, NAD-binding.
 
  
 0.923
ACV35328.1
PFAM: FAD linked oxidase domain protein; KEGG: dar:Daro_3315 FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal.
   
 0.920
ACV35329.1
PFAM: FAD linked oxidase domain protein; KEGG: har:HEAR0285 glycolate oxidase subunit GlcE.
   
 0.920
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
 
  
 0.919
ACV35795.1
PFAM: HpcH/HpaI aldolase; KEGG: rrs:RoseRS_4173 HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
    
 0.916
ACV37104.1
TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: dar:Daro_3098 isocitrate lyase.
     
 0.916
ACV34012.1
KEGG: dar:Daro_3317 xylose isomerase-like TIM barrel; TIGRFAM: hydroxypyruvate isomerase; PFAM: Xylose isomerase domain protein TIM barrel; Belongs to the hyi family.
   
 
 0.914
ACV35330.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: eba:ebA4492 glycolate oxidase iron-sulfur subunit.
    
 0.909
Your Current Organism:
Accumulibacter phosphatis
NCBI taxonomy Id: 522306
Other names: Accumulibacter phosphatis UW-1, C. Accumulibacter phosphatis clade IIA str. UW-1, Candidatus Accumulibacter phosphatis Type IIA str. UW-1, Candidatus Accumulibacter phosphatis clade IIA str. UW-1, Candidatus Accumulibacter phosphatis clade IIA strain UW-1
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