Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD66890.1PFAM: FAD dependent oxidoreductase; KEGG: gur:Gura_0933 amine oxidase. (394 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.994
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
 0.990
ADD67604.1
Flavodoxin-like protein; KEGG: kpe:KPK_5329 protoporphyrinogen oxidase.
     
 0.906
ADD67811.1
Hypothetical protein; KEGG: bba:Bd2899 protoporphyrinogen oxidase.
     
 0.906
ADD69669.1
KEGG: mca:MCA1124 competence protein F.
  
    0.671
ADD69660.1
Porphobilinogen synthase; KEGG: gme:Gmet_0189 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
  
 0.626
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.566
ADD69659.1
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.505
ADD67808.1
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: dds:Ddes_1441 redoxin domain protein.
  
  
 0.430
ADD69705.1
PFAM: Prephenate dehydrogenase; KEGG: glo:Glov_2149 prephenate dehydrogenase.
   
    0.428
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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