Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD66891.1KEGG: dds:Ddes_0615 hypothetical protein. (119 aa)    
Predicted Functional Partners:
napA
Molybdopterin oxidoreductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
     
 0.820
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.791
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.753
ADD67342.1
KEGG: sat:SYN_01836 MreB-like ATPase involved in cell division.
  
 0.745
ADD67453.1
KEGG: sat:SYN_01836 MreB-like ATPase involved in cell division.
  
 0.745
ADD69479.1
PFAM: Heat shock protein 70; KEGG: sat:SYN_01983 chaperone protein.
  
 0.745
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.745
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.737
ADD69258.1
PFAM: Ankyrin; KEGG: inversin protein alternative isoform.
   
 0.710
rplQ
KEGG: aeh:Mlg_0484 50S ribosomal protein L17P; TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17.
  
 
 0.707
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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