Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (234 aa)    
Predicted Functional Partners:
ADD66952.1
PFAM: cobalbumin biosynthesis protein; KEGG: dat:HRM2_02230 CobU.
 
 
 0.997
cobT
Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 
 0.990
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
   
 0.982
ADD66957.1
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: dat:HRM2_45640 hypothetical protein.
    
  0.979
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.943
ADD66964.1
TIGRFAM: precorrin-3B C17-methyltransferase; KEGG: vsp:VS_2667 precorrin-3B methylase CobJ; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
  
 0.942
ADD67926.1
ATP/cobalamin adenosyltransferase; KEGG: bgl:bglu_1g06200 putative ATP:cob(I)alamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.930
ADD66955.1
PFAM: aminotransferase class I and II; KEGG: dal:Dalk_0456 aminotransferase class I and II.
 
   
 0.884
ADD66961.1
KEGG: tau:Tola_1681 cobyrinic acid a,c-diamide synthase; TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; Cobyrinic acid ac-diamide synthase.
 
  
 0.844
ADD66963.1
PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: kpn:KPN_03191 cobalt-precorrin-6x reductase.
 
  
 0.818
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.