Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD66958.1KEGG: ppd:Ppro_3502 precorrin-2 C20- methyltransferase; TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. (228 aa)    
Predicted Functional Partners:
ADD66964.1
TIGRFAM: precorrin-3B C17-methyltransferase; KEGG: vsp:VS_2667 precorrin-3B methylase CobJ; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
 0.999
ADD66969.1
Sirohydrochlorin cobaltochelatase; KEGG: dat:HRM2_07680 CbiK1; PFAM: anaerobic cobalt chelatase.
 
 0.999
ADD66962.1
KEGG: vsp:VS_2662 precorrin-8X methylmutase CbiC; PFAM: Precorrin-8X methylmutase CbiC/CobH.
 
  
 0.992
ADD66963.1
PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: kpn:KPN_03191 cobalt-precorrin-6x reductase.
 
  
 0.984
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.983
ADD66965.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: pca:Pcar_0472 cobalamin biosynthesis protein CbiG.
 
  
 0.981
ADD66960.1
TIGRFAM: siroheme synthase; KEGG: vha:VIBHAR_02359 hypothetical protein.
 
  
 0.975
ADD66961.1
KEGG: tau:Tola_1681 cobyrinic acid a,c-diamide synthase; TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; Cobyrinic acid ac-diamide synthase.
  
 0.974
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
  
 0.974
ADD66975.1
uroporphyrin-III C-methyltransferase; KEGG: dde:Dde_2837 uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
  
 0.972
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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