Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (477 aa)    
Predicted Functional Partners:
ADD66962.1
KEGG: vsp:VS_2662 precorrin-8X methylmutase CbiC; PFAM: Precorrin-8X methylmutase CbiC/CobH.
  
 0.998
ADD66961.1
KEGG: tau:Tola_1681 cobyrinic acid a,c-diamide synthase; TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; Cobyrinic acid ac-diamide synthase.
  
 0.997
ADD66964.1
TIGRFAM: precorrin-3B C17-methyltransferase; KEGG: vsp:VS_2667 precorrin-3B methylase CobJ; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
  
 0.995
ADD66952.1
PFAM: cobalbumin biosynthesis protein; KEGG: dat:HRM2_02230 CobU.
  
 0.994
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 0.992
ADD66958.1
KEGG: ppd:Ppro_3502 precorrin-2 C20- methyltransferase; TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.983
ADD66963.1
PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: kpn:KPN_03191 cobalt-precorrin-6x reductase.
 
  
 0.969
ADD66966.1
TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: gur:Gura_0039 precorrin-4 C11- methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
  
 0.963
ADD66955.1
PFAM: aminotransferase class I and II; KEGG: dal:Dalk_0456 aminotransferase class I and II.
  
 0.959
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.943
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
Server load: low (8%) [HD]