Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADD66976.1TIGRFAM: PAS sensor protein; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; PAS fold domain protein; KEGG: gur:Gura_1729 signal transduction histidine kinase; SMART: PAS domain containing protein. (789 aa)    
Predicted Functional Partners:
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
  
 0.827
ADD66979.1
PFAM: MCP methyltransferase CheR-type; KEGG: gme:Gmet_2420 MCP methyltransferase, CheR- type; SMART: MCP methyltransferase CheR-type.
 
  
 0.823
cheD
CheD, stimulates methylation of MCP protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
     0.802
ADD66987.1
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; KEGG: gsu:GSU1249 sensory box histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver.
 
 
 0.802
ADD69631.1
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: gur:Gura_2373 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein.
 
 
 0.730
ADD67940.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; KEGG: gme:Gmet_1707 PAS/PAC sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
  
 
 0.700
ADD68190.1
Multi-sensor hybrid histidine kinase; KEGG: vcj:VCD_002990 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein.
  
 
 0.694
ADD68495.1
Integral membrane sensor hybrid histidine kinase; KEGG: sse:Ssed_2865 signal transduction histidine kinase-like protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein.
  
 
 0.691
ADD68821.1
Multi-sensor hybrid histidine kinase; KEGG: swp:swp_2315 PAS domain protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein.
   
 
 0.688
ADD66950.1
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; KEGG: wsu:WS0415 sensor kinase of two-component regulatory system; SMART: ATP-binding region ATPase domain protein; GAF domain protein; PAS domain containing protein.
 
 
 
 0.685
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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