Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ADD66981.1KEGG: dvm:DvMF_1209 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer. (679 aa)    
Predicted Functional Partners:
ADD66980.1
KEGG: glo:Glov_1734 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
  0.989
ADD66982.1
KEGG: geo:Geob_2260 CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; SMART: CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein.
 
 0.986
ADD69604.1
CheA signal transduction histidine kinase; KEGG: cla:Cla_1369 chemotaxis protein CheA; PFAM: CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; response regulator receiver; ATP-binding region ATPase domain protein; SMART: CheW domain protein; response regulator receiver; Hpt domain protein; ATP-binding region ATPase domain protein.
 
 0.976
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.971
ADD66979.1
PFAM: MCP methyltransferase CheR-type; KEGG: gme:Gmet_2420 MCP methyltransferase, CheR- type; SMART: MCP methyltransferase CheR-type.
 
 0.969
ADD66983.1
KEGG: dma:DMR_19040 chemotaxis protein CheY; PFAM: response regulator receiver; SMART: response regulator receiver.
 
  0.965
cheD
CheD, stimulates methylation of MCP protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  0.963
ADD68198.1
CheW protein; KEGG: dma:DMR_20770 chemotaxis protein CheW; PFAM: CheW domain protein; SMART: CheW domain protein.
 
  0.958
ADD69014.1
KEGG: dvm:DvMF_0284 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
  0.957
ADD69477.1
CheW protein; KEGG: bgl:bglu_2g19940 CheW; PFAM: CheW domain protein; SMART: CheW domain protein.
 
  0.956
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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