Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD66988.1KEGG: ppd:Ppro_0378 two component, sigma54 specific, fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase. (460 aa)    
Predicted Functional Partners:
ADD66987.1
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; KEGG: gsu:GSU1249 sensory box histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver.
 
 
 0.835
ADD68081.1
KEGG: bba:Bd0843 RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor.
 
   
 0.778
ADD66982.1
KEGG: geo:Geob_2260 CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; SMART: CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein.
  
 
 0.641
ADD66986.1
KEGG: gsu:GSU0598 sigma-54 dependent DNA-binding response regulator; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
   0.578
cheD
CheD, stimulates methylation of MCP protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
  
  
 0.537
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
  
 0.524
ADD69600.1
KEGG: ccv:CCV52592_1439 flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein.
  
  
 0.523
ADD66980.1
KEGG: glo:Glov_1734 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
  
    0.509
ADD66984.1
KEGG: geo:Geob_2258 anti-sigma-factor antagonist.
  
    0.492
ADD66985.1
KEGG: dar:Daro_1140 chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer.
  
    0.487
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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