Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
ADD67019.1Transcriptional regulator, LacI family; KEGG: oan:Oant_4373 regulatory protein LacI; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI. (351 aa)    
Predicted Functional Partners:
ADD68090.1
Phosphotransferase system, phosphocarrier protein HPr; KEGG: gme:Gmet_1288 HPrNtr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr.
   
 
 0.921
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.902
ADD66909.1
PFAM: ferredoxin-dependent glutamate synthase; 4Fe- 4S ferredoxin iron-sulfur binding domain protein; KEGG: gme:Gmet_1756 glutamate synthase (NADPH) GltB2 subunit.
  
 
 
 0.860
ADD67023.1
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: vha:VIBHAR_06143 D-ribose transporter subunit RbsB.
 
  
 0.778
ADD67022.1
PFAM: inner-membrane translocator; KEGG: vha:VIBHAR_06144 ribose ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.769
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.766
rbsA
ABC transporter related protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
  
 0.765
ADD68435.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pca:Pcar_2600 glutamate synthase, alpha subunit-like.
    
 
 0.741
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
    
   0.727
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.727
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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