Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD67138.1PFAM: MscS Mechanosensitive ion channel; KEGG: pca:Pcar_2988 putative small-conductance mechanosensitive channel. (600 aa)    
Predicted Functional Partners:
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.786
ADD67140.1
PFAM: Peptidase M23; KEGG: dal:Dalk_0953 peptidase M23.
     
 0.563
ADD67137.1
KEGG: nis:NIS_1563 general secretory pathway protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase.
       0.555
ADD67136.1
PFAM: Type II secretion system F domain; KEGG: ilo:IL0371 type II secretory pathway.
       0.532
ADD67905.1
PFAM: protein of unknown function DUF785; KEGG: abu:Abu_2189 hypothetical protein.
 
    0.423
ADD67807.1
PFAM: Mg2 transporter protein CorA family protein; KEGG: ftn:FTN_0005 divalent inorganic cation transporter.
 
   
 0.409
ADD69701.1
PFAM: sodium/calcium exchanger membrane region; KEGG: rfr:Rfer_3080 sodium/calcium exchanger membrane protein.
 
     0.403
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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