Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD67221.1KEGG: glo:Glov_3064 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC). (75 aa)    
Predicted Functional Partners:
ADD67220.1
PFAM: hydrogenase formation HypD protein; KEGG: dps:DP0579 hydrogenase accessory protein HypD.
 
 
 0.998
ADD67081.1
KEGG: slo:Shew_1756 hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein.
 
 
 0.983
ADD69734.1
KEGG: gme:Gmet_0119 hydrogenase maturation protein HypF; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein.
 
 
 0.916
ADD69175.1
KEGG: gsu:GSU0305 hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
 
  
 0.903
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.786
ADD67222.1
PFAM: Rhomboid family protein; KEGG: dal:Dalk_3454 rhomboid family protein.
       0.779
ADD67218.1
Hypothetical protein.
       0.773
hflX
GTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
       0.773
ADD69308.1
KEGG: dps:DP0159 cytochrome-c3 hydrogenase (NiFeSe), large subunit; PFAM: nickel-dependent hydrogenase large subunit.
 
 
 0.773
ADD68789.1
PFAM: cobalamin synthesis protein P47K; KEGG: glo:Glov_1036 cobalamin synthesis protein P47K.
  
  
 0.674
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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