Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
ADD67245.1PFAM: peptidase M24; creatinase; KEGG: pca:Pcar_2614 Xaa-Pro aminopeptidase. (394 aa)    
Predicted Functional Partners:
ADD67244.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
 0.825
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.743
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.539
msrB
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
   
 0.525
ADD68188.1
TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; KEGG: gur:Gura_2382 cofactor-independent phosphoglycerate mutase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein.
  
     0.492
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.490
ADD68298.1
Polynucleotide adenylyltransferase region; KEGG: gur:Gura_2246 CBS domain-containing protein; PFAM: Polynucleotide adenylyltransferase region; phosphoesterase DHHA1; CBS domain containing protein; phosphoesterase RecJ domain protein; SMART: CBS domain containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
  
 0.471
ADD68693.1
KEGG: glo:Glov_3260 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12- binding domain protein.
     
 0.440
pheT
KEGG: sat:SYN_01723 phenylalanyl-tRNA synthetase beta chain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
  
  
 0.439
ADD69275.1
PFAM: nitroreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dps:DP1356 ferredoxin.
 
  
 0.434
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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