Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD67486.1PFAM: integrase family protein; KEGG: ppd:Ppro_1126 phage integrase family protein; Belongs to the 'phage' integrase family. (342 aa)    
Predicted Functional Partners:
ADD67487.1
Hypothetical protein.
       0.773
ADD67485.1
Putative transcriptional regulator; PFAM: AAA-4 family protein; KEGG: hso:HS_0100 transcriptional regulator.
       0.580
ADD69669.1
KEGG: mca:MCA1124 competence protein F.
   
    0.537
ADD68913.1
PFAM: phosphoribosyltransferase; KEGG: avn:Avin_47930 xanthine phosphoribosyltransferase.
   
    0.534
ADD67488.1
KEGG: nis:NIS_1322 hypothetical protein.
       0.529
ADD69705.1
PFAM: Prephenate dehydrogenase; KEGG: glo:Glov_2149 prephenate dehydrogenase.
  
    0.507
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
   
 0.506
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.471
ADD69509.1
KEGG: gur:Gura_4392 cell divisionFtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase.
 
   
 0.452
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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