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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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glnDUTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (863 aa)    
Predicted Functional Partners:
ADD68452.1
PFAM: nitrogen regulatory protein P-II; KEGG: pca:Pcar_1500 regulatory protein P-II for glutamine synthetase.
 
 
 0.980
ADD69009.1
PFAM: nitrogen regulatory protein P-II; KEGG: geo:Geob_1818 nitrogen regulatory protein P- II; Belongs to the P(II) protein family.
 
 
 0.977
ADD69521.1
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
 
   
 0.826
ADD67611.1
TIGRFAM: PAS sensor protein; PFAM: PAS fold domain protein; KEGG: dal:Dalk_0572 PAS/PAC sensor hybrid histidine kinase; SMART: PAS domain containing protein.
     
 0.778
ADD67613.1
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
       0.770
ADD68451.1
KEGG: gur:Gura_2228 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
 
   
 0.644
ADD67610.1
KEGG: abu:Abu_1092 hypothetical protein.
 
     0.610
ADD69058.1
KEGG: gbm:Gbem_0839 outer membrane protein assembly complex, YaeT protein; TIGRFAM: outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat protein.
 
    0.560
ADD66909.1
PFAM: ferredoxin-dependent glutamate synthase; 4Fe- 4S ferredoxin iron-sulfur binding domain protein; KEGG: gme:Gmet_1756 glutamate synthase (NADPH) GltB2 subunit.
     
 0.550
ADD66961.1
KEGG: tau:Tola_1681 cobyrinic acid a,c-diamide synthase; TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; Cobyrinic acid ac-diamide synthase.
   
    0.540
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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