Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (529 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.941
ADD68566.1
KEGG: glo:Glov_1379 type I citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.939
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.938
ADD69092.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.937
ADD67833.1
TIGRFAM: pyruvate kinase; KEGG: dal:Dalk_3774 pyruvate kinase; PFAM: Pyruvate kinase barrel; HpcH/HpaI aldolase; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
    
 0.936
ADD68591.1
TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; KEGG: dat:HRM2_06280 OadB1; PFAM: Na+transporting methylmalonyl- CoA/oxaloacetate decarboxylase beta subunit.
    
 0.920
ADD68826.1
KEGG: sfu:Sfum_2438 aspartate ammonia-lyase; TIGRFAM: aspartate ammonia-lyase; PFAM: fumarate lyase; Fumarase C-like.
  
 
 0.917
ADD69562.1
TIGRFAM: pyruvate, phosphate dikinase; KEGG: gur:Gura_3671 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; PEP-utilising protein mobile region; PEP- utilizing protein; Belongs to the PEP-utilizing enzyme family.
     
 0.910
ADD68457.1
KEGG: pca:Pcar_0377 NifJ-like oxidoreductase, Fe-S subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain.
    
 0.896
ADD68693.1
KEGG: glo:Glov_3260 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12- binding domain protein.
    
 0.883
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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