STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADD67649.1KEGG: nis:NIS_0533 oligopeptidase A; PFAM: peptidase M3A and M3B thimet/oligopeptidase F. (647 aa)    
Predicted Functional Partners:
ADD67526.1
PFAM: protein of unknown function DUF752; KEGG: wsu:WS0458 hypothetical protein.
 
     0.476
ADD69018.1
KEGG: noc:Noc_1357 hypothetical protein; PFAM: protein of unknown function DUF399; SMART: PDZ/DHR/GLGF domain protein.
 
 
 
 0.467
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
  
 0.445
ADD67650.1
Transcriptional regulator, Crp/Fnr family; KEGG: dar:Daro_1294 cyclic nucleotide-binding: regulatory protein, Crp; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
    0.444
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.428
ADD67652.1
Phosphomannomutase; KEGG: mxa:MXAN_6499 phosphomannomutase/phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II.
  
    0.426
ADD67654.1
KEGG: scl:sce0859 hypothetical protein.
  
  
 0.422
ispG
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.417
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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