Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD67650.1Transcriptional regulator, Crp/Fnr family; KEGG: dar:Daro_1294 cyclic nucleotide-binding: regulatory protein, Crp; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding. (221 aa)    
Predicted Functional Partners:
ADD67941.1
KEGG: dar:Daro_2902 response regulator receiver; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver.
  
 
 0.919
ADD67652.1
Phosphomannomutase; KEGG: mxa:MXAN_6499 phosphomannomutase/phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II.
  
    0.739
ispG
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.737
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.716
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.704
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.702
ADD68328.1
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.693
ADD67924.1
KEGG: glo:Glov_1969 adenylate/guanylate cyclase with CHASE sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class- 3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 0.685
ADD67654.1
KEGG: scl:sce0859 hypothetical protein.
 
   
 0.608
ADD67653.1
Putative anti-sigma regulatory factor, serine/threonine protein kinase; KEGG: cvi:CV_0472 two-component response regulator.
       0.539
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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