close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADD67653.1Putative anti-sigma regulatory factor, serine/threonine protein kinase; KEGG: cvi:CV_0472 two-component response regulator. (270 aa)    
Predicted Functional Partners:
ADD69609.1
KEGG: geo:Geob_2165 PBS lyase heat domain protein repeat-containing protein; PFAM: PBS lyase HEAT domain protein repeat- containing protein; SMART: PBS lyase HEAT domain protein repeat- containing protein.
 
 
 0.904
ADD67940.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; KEGG: gme:Gmet_1707 PAS/PAC sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
  
  
 0.868
ADD69607.1
KEGG: geo:Geob_0264 putative PAS/PAC sensor protein; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
 
 
 0.863
ADD69460.1
Protein serine/threonine phosphatase; KEGG: pub:SAR11_0064 sigma factor SigB regulation protein; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
 
 
 0.857
ADD66984.1
KEGG: geo:Geob_2258 anti-sigma-factor antagonist.
  
 
 0.837
ADD67983.1
KEGG: noc:Noc_2976 anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.837
ADD68668.1
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: dma:DMR_19140 anti-sigma factor antagonist family protein.
  
 
 0.837
ADD68669.1
Anti-sigma-factor antagonist; KEGG: pca:Pcar_1874 anti-anti-sigma regulatory factor; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.837
ADD69608.1
Anti-sigma-factor antagonist; KEGG: pca:Pcar_1874 anti-anti-sigma regulatory factor; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.837
ADD67654.1
KEGG: scl:sce0859 hypothetical protein.
 
     0.827
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
Server load: medium (46%) [HD]