Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADD67972.1HflC protein; HflC and HflK could regulate a protease. (286 aa)    
Predicted Functional Partners:
ADD67973.1
HflK protein; HflC and HflK could encode or regulate a protease.
     0.991
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.861
ADD67781.1
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 
 0.711
ADD67974.1
KEGG: geo:Geob_2386 translation elongation factor G; TIGRFAM: translation elongation factor G; small GTP- binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; elongation factor G domain IV.
  
 
 0.582
yidC
Membrane protein insertase, YidC/Oxa1 family; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
 
 0.540
ADD67309.1
PFAM: protein of unknown function DUF107; KEGG: ade:Adeh_2369 nodulation efficiency protein NfeD.
 
    0.461
ADD67975.1
Hypothetical protein.
       0.456
ADD67641.1
PFAM: peptidase M16 domain protein; KEGG: bba:Bd3869 zinc protease; Belongs to the peptidase M16 family.
  
 0.454
ADD67749.1
PFAM: peptidase M16 domain protein; KEGG: swp:swp_4956 probable zinc protease; Belongs to the peptidase M16 family.
  
 0.454
ADD68123.1
PFAM: peptidase M16 domain protein; KEGG: wpi:WPa_0591 peptidase, M16 family.
  
 0.454
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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