STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADD67988.1Malate dehydrogenase (oxaloacetate- decarboxylating); KEGG: gsu:GSU2308 malate oxidoreductase; PFAM: malic protein domain protein; malic protein NAD-binding. (446 aa)    
Predicted Functional Partners:
ADD68457.1
KEGG: pca:Pcar_0377 NifJ-like oxidoreductase, Fe-S subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain.
    
 0.947
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.945
ADD67833.1
TIGRFAM: pyruvate kinase; KEGG: dal:Dalk_3774 pyruvate kinase; PFAM: Pyruvate kinase barrel; HpcH/HpaI aldolase; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 0.941
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.938
ADD68757.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: ppd:Ppro_0549 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
    
 0.936
ADD69120.1
KEGG: dma:DMR_34300 L-tartrate dehydratase alpha subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region.
 
 
 0.934
ADD69121.1
TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; KEGG: acp:A2cp1_0286 Fe-S type hydro-lyase tartrate/fumarate beta region; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region.
 
 
 0.933
ADD69092.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.930
ADD68300.1
PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: geo:Geob_2882 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), phosphate acetyltransferase.
 
 
0.927
ADD68591.1
TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; KEGG: dat:HRM2_06280 OadB1; PFAM: Na+transporting methylmalonyl- CoA/oxaloacetate decarboxylase beta subunit.
    
 0.913
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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