STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADD68091.1Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (580 aa)    
Predicted Functional Partners:
ADD68090.1
Phosphotransferase system, phosphocarrier protein HPr; KEGG: gme:Gmet_1288 HPrNtr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr.
 
 0.999
ADD68083.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: pca:Pcar_1936 phosphotransferase system enzyme IIA, regulates nitrogen metabolism.
 
   
 0.959
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
   
 0.953
ADD68086.1
PFAM: PTS system fructose subfamily IIA component; KEGG: gsu:GSU1883 PTS system, IIA component, putative.
 
  
 0.945
ADD68087.1
PFAM: PTS system sorbose subfamily IIB component; KEGG: sat:SYN_02845 phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB.
 
  
 0.925
ADD68089.1
PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: afw:Anae109_0156 PTS system mannose/fructose/sorbose family IID component.
 
   
 0.912
hpf
Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
  
 0.851
ADD68081.1
KEGG: bba:Bd0843 RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor.
  
  
 0.844
ADD68085.1
Conserved hypothetical protein; Displays ATPase and GTPase activities.
     
 0.827
ADD68088.1
Hypothetical protein; KEGG: sat:SYN_02846 phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC.
       0.820
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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