Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD68166.1PFAM: glycosyl transferase family 2; KEGG: sat:SYN_00376 glycosyltransferase involved in cell wall biogenesis. (219 aa)    
Predicted Functional Partners:
ADD68169.1
PFAM: Protein of unknown function DUF2064; KEGG: dvu:DVU1891 hypothetical protein.
     0.994
ADD68167.1
PFAM: SNARE associated Golgi protein; KEGG: gbm:Gbem_0458 SNARE associated Golgi protein.
 
   
 0.948
ADD68168.1
PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; HI0933 family protein; KEGG: aeh:Mlg_0751 pyridine nucleotide-disulphide oxidoreductase dimerisation region.
 
     0.911
ADD68170.1
KEGG: gur:Gura_2810 S-isoprenylcysteine methyltransferase-like protein.
       0.773
ADD68171.1
PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein domain protein; PEP-utilising protein mobile region; GAF domain protein; KEGG: geo:Geob_3492 putative phytochrome sensor protein; SMART: GAF domain protein; Belongs to the PEP-utilizing enzyme family.
       0.773
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.691
ADD68164.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.686
mqnD
Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
     
 0.610
ADD68173.1
PFAM: Mammalian cell entry related domain protein; KEGG: sat:SYN_00409 ABC-type transport system involved in resistance to organic solvents, periplasmic component.
       0.608
ADD68174.1
ABC transporter related protein; KEGG: sat:SYN_00410 ABC-type transport system, ATP- binding component; PFAM: ABC transporter related; SMART: AAA ATPase.
       0.599
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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