| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADD67301.1 | ADD68167.1 | Dacet_0503 | Dacet_1397 | KEGG: ebr:ECB_01718 exonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | PFAM: SNARE associated Golgi protein; KEGG: gbm:Gbem_0458 SNARE associated Golgi protein. | 0.658 |
| ADD68164.1 | ADD68166.1 | Dacet_1394 | Dacet_1396 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | PFAM: glycosyl transferase family 2; KEGG: sat:SYN_00376 glycosyltransferase involved in cell wall biogenesis. | 0.686 |
| ADD68164.1 | ADD68167.1 | Dacet_1394 | Dacet_1397 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | PFAM: SNARE associated Golgi protein; KEGG: gbm:Gbem_0458 SNARE associated Golgi protein. | 0.719 |
| ADD68164.1 | ADD68168.1 | Dacet_1394 | Dacet_1398 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; HI0933 family protein; KEGG: aeh:Mlg_0751 pyridine nucleotide-disulphide oxidoreductase dimerisation region. | 0.836 |
| ADD68164.1 | ADD68169.1 | Dacet_1394 | Dacet_1399 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | PFAM: Protein of unknown function DUF2064; KEGG: dvu:DVU1891 hypothetical protein. | 0.701 |
| ADD68164.1 | ADD68170.1 | Dacet_1394 | Dacet_1400 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | KEGG: gur:Gura_2810 S-isoprenylcysteine methyltransferase-like protein. | 0.686 |
| ADD68164.1 | ADD68171.1 | Dacet_1394 | Dacet_1401 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein domain protein; PEP-utilising protein mobile region; GAF domain protein; KEGG: geo:Geob_3492 putative phytochrome sensor protein; SMART: GAF domain protein; Belongs to the PEP-utilizing enzyme family. | 0.698 |
| ADD68164.1 | thyA | Dacet_1394 | Dacet_1395 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.998 |
| ADD68166.1 | ADD68164.1 | Dacet_1396 | Dacet_1394 | PFAM: glycosyl transferase family 2; KEGG: sat:SYN_00376 glycosyltransferase involved in cell wall biogenesis. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.686 |
| ADD68166.1 | ADD68167.1 | Dacet_1396 | Dacet_1397 | PFAM: glycosyl transferase family 2; KEGG: sat:SYN_00376 glycosyltransferase involved in cell wall biogenesis. | PFAM: SNARE associated Golgi protein; KEGG: gbm:Gbem_0458 SNARE associated Golgi protein. | 0.948 |
| ADD68166.1 | ADD68168.1 | Dacet_1396 | Dacet_1398 | PFAM: glycosyl transferase family 2; KEGG: sat:SYN_00376 glycosyltransferase involved in cell wall biogenesis. | PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; HI0933 family protein; KEGG: aeh:Mlg_0751 pyridine nucleotide-disulphide oxidoreductase dimerisation region. | 0.911 |
| ADD68166.1 | ADD68169.1 | Dacet_1396 | Dacet_1399 | PFAM: glycosyl transferase family 2; KEGG: sat:SYN_00376 glycosyltransferase involved in cell wall biogenesis. | PFAM: Protein of unknown function DUF2064; KEGG: dvu:DVU1891 hypothetical protein. | 0.994 |
| ADD68166.1 | ADD68170.1 | Dacet_1396 | Dacet_1400 | PFAM: glycosyl transferase family 2; KEGG: sat:SYN_00376 glycosyltransferase involved in cell wall biogenesis. | KEGG: gur:Gura_2810 S-isoprenylcysteine methyltransferase-like protein. | 0.773 |
| ADD68166.1 | ADD68171.1 | Dacet_1396 | Dacet_1401 | PFAM: glycosyl transferase family 2; KEGG: sat:SYN_00376 glycosyltransferase involved in cell wall biogenesis. | PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein domain protein; PEP-utilising protein mobile region; GAF domain protein; KEGG: geo:Geob_3492 putative phytochrome sensor protein; SMART: GAF domain protein; Belongs to the PEP-utilizing enzyme family. | 0.773 |
| ADD68166.1 | thyA | Dacet_1396 | Dacet_1395 | PFAM: glycosyl transferase family 2; KEGG: sat:SYN_00376 glycosyltransferase involved in cell wall biogenesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.691 |
| ADD68167.1 | ADD67301.1 | Dacet_1397 | Dacet_0503 | PFAM: SNARE associated Golgi protein; KEGG: gbm:Gbem_0458 SNARE associated Golgi protein. | KEGG: ebr:ECB_01718 exonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | 0.658 |
| ADD68167.1 | ADD68164.1 | Dacet_1397 | Dacet_1394 | PFAM: SNARE associated Golgi protein; KEGG: gbm:Gbem_0458 SNARE associated Golgi protein. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.719 |
| ADD68167.1 | ADD68166.1 | Dacet_1397 | Dacet_1396 | PFAM: SNARE associated Golgi protein; KEGG: gbm:Gbem_0458 SNARE associated Golgi protein. | PFAM: glycosyl transferase family 2; KEGG: sat:SYN_00376 glycosyltransferase involved in cell wall biogenesis. | 0.948 |
| ADD68167.1 | ADD68168.1 | Dacet_1397 | Dacet_1398 | PFAM: SNARE associated Golgi protein; KEGG: gbm:Gbem_0458 SNARE associated Golgi protein. | PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; HI0933 family protein; KEGG: aeh:Mlg_0751 pyridine nucleotide-disulphide oxidoreductase dimerisation region. | 0.991 |
| ADD68167.1 | ADD68169.1 | Dacet_1397 | Dacet_1399 | PFAM: SNARE associated Golgi protein; KEGG: gbm:Gbem_0458 SNARE associated Golgi protein. | PFAM: Protein of unknown function DUF2064; KEGG: dvu:DVU1891 hypothetical protein. | 0.945 |
