STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADD68185.1C_GCAxxG_C_C family protein; KEGG: gsu:GSU0395 hypothetical protein; TIGRFAM: C_GCAxxG_C_C family protein; PFAM: C_GCAxxG_C_C family protein. (150 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.662
ADD69708.1
Chorismate mutase; KEGG: gur:Gura_1462 prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase.
     
 0.539
msrB
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.537
ADD68184.1
PFAM: periplasmic binding protein; KEGG: nam:NAMH_0731 HemV-3 iron (III) ABC transporter, ATP-binding protein.
       0.533
ADD68523.1
KEGG: glo:Glov_3529 C_GCAxxG_C_C family protein; TIGRFAM: C_GCAxxG_C_C family protein; PFAM: C_GCAxxG_C_C family protein.
  
     0.522
ADD67223.1
KEGG: nam:NAMH_1292 hypothetical protein; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA family protein; Belongs to the sulfur carrier protein TusA family.
 
     0.506
ADD68095.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.476
ADD69501.1
PFAM: protein of unknown function DUF116; KEGG: ppd:Ppro_0512 hypothetical protein.
  
     0.413
ADD68563.1
Hypothetical protein; KEGG: vfi:VF_A0099 glutamate synthase.
 
     0.409
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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