Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADD68276.1Transcriptional regulator, XRE family; KEGG: aha:AHA_0244 DNA-binding protein; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. (182 aa)    
Predicted Functional Partners:
ADD68277.1
PFAM: Proline dehydrogenase; KEGG: dps:DP2492 proline dehydrogenase.
       0.727
ADD68278.1
KEGG: dat:HRM2_16880 PutA2; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase.
  
  
 0.686
ADD68868.1
Transcriptional regulator, GntR family; KEGG: rhi:NGR_b21910 transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
  
  
 0.667
ADD67422.1
KEGG: gur:Gura_4388 helix-turn-helix domain- containing protein; PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; SMART: helix-turn-helix domain protein.
  
  
 0.595
ADD69708.1
Chorismate mutase; KEGG: gur:Gura_1462 prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase.
  
  
 0.563
ADD69579.1
PFAM: Silent information regulator protein Sir2; KEGG: sat:SYN_01020 Sir2 family NAD-dependent deacetylase.
  
    0.555
ADD69641.1
PFAM: Silent information regulator protein Sir2; KEGG: nis:NIS_0515 Sir2 family transcriptional regulator.
  
    0.555
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.505
ADD69384.1
GntR domain protein; KEGG: spc:Sputcn32_3384 regulatory protein GntR, HTH; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
 
  
 0.479
ADD68385.1
KEGG: dal:Dalk_3942 plasmid maintenance system antidote protein, XRE family; PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; SMART: helix-turn-helix domain protein.
  
  
 0.464
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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