Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD68659.1PFAM: Peptidase M23; KEGG: pca:Pcar_2472 metalloendopeptidase-like membrane protein. (382 aa)    
Predicted Functional Partners:
ADD68661.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
       0.817
ADD68660.1
PFAM: SNARE associated Golgi protein; KEGG: abu:Abu_2024 hypothetical protein.
       0.816
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.816
ADD68663.1
TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: gur:Gura_2037 hemolysin A; SMART: RNA-binding S4 domain protein.
       0.816
dxs
Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
       0.816
ADD68665.1
PFAM: Polyprenyl synthetase; KEGG: glo:Glov_2183 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
       0.791
xseB
Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
       0.791
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
       0.776
ADD68668.1
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: dma:DMR_19140 anti-sigma factor antagonist family protein.
       0.776
ADD68574.1
PFAM: Peptidase M23; KEGG: glo:Glov_1921 peptidase M23.
 
   
 0.744
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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