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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADD68731.1KEGG: gur:Gura_3741 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (360 aa)    
Predicted Functional Partners:
ADD68732.1
Two component, sigma54 specific, transcriptional regulator, Fis family; KEGG: gsu:GSU1320 sigma-54 dependent DNA-binding response regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase.
 
 
   0.911
ADD68242.1
Histidine kinase; KEGG: abu:Abu_0433 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
  
 
   0.794
ADD68489.1
KEGG: abu:Abu_0418 two-component response regulator; PFAM: response regulator receiver; SMART: response regulator receiver.
  
 
   0.789
ADD69458.1
Response regulator receiver protein; KEGG: dal:Dalk_1576 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; SMART: response regulator receiver.
  
 
   0.789
ADD69123.1
KEGG: gsu:GSU0598 sigma-54 dependent DNA-binding response regulator; PFAM: response regulator receiver; SMART: response regulator receiver.
  
 
   0.787
ADD67772.1
KEGG: glo:Glov_0569 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
  
   0.781
ADD67840.1
KEGG: dat:HRM2_10420 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
   0.778
ADD69664.1
KEGG: hch:HCH_01618 signal transduction histidine kinase regulating C4-dicarboxylate transport system; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 
   0.778
ADD68730.1
KEGG: dma:DMR_19590 putative ABC transporter ATP- binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
      0.773
ADD68729.1
PFAM: protein of unknown function DUF214; KEGG: dma:DMR_19600 putative ABC transporter permease protein.
       0.752
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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