Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD68842.1PFAM: NLPA lipoprotein; KEGG: bbr:BB4519 hypothetical protein. (271 aa)    
Predicted Functional Partners:
ADD68843.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bcm:Bcenmc03_1019 binding-protein-dependent transport systems inner membrane component.
 0.999
metN
ABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 
 0.998
ADD69278.1
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: gsu:GSU1183 O-acetyl-L-homoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein.
  
    0.609
ADD69493.1
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: pca:Pcar_1453 O-acetylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein.
  
    0.609
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.564
ADD68699.1
TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: ank:AnaeK_2769 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.506
ADD67644.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.476
ADD69168.1
KEGG: pca:Pcar_2042 membrane-bound lytic murein transglycosylase D precursor; PFAM: Lytic transglycosylase catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
     
 0.471
ADD68841.1
Transcriptional regulator, AraC family; KEGG: smd:Smed_4732 helix-turn-helix domain- containing protein; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain.
       0.463
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
  
 0.456
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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