Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD68932.1KEGG: sfu:Sfum_3992 response regulator receiver and unknown domain protein; PFAM: response regulator receiver; SMART: response regulator receiver. (231 aa)    
Predicted Functional Partners:
ADD68931.1
KEGG: sfu:Sfum_3991 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 0.980
ADD68162.1
KEGG: sfu:Sfum_3991 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 
 0.901
ADD67940.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; KEGG: gme:Gmet_1707 PAS/PAC sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
     
 0.526
ADD68930.1
TIGRFAM: flavocytochrome c; KEGG: saz:Sama_0611 fumarate reductase flavoprotein subunit precursor; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
       0.508
ADD68929.1
Hypothetical protein; KEGG: sse:Ssed_0297 flavocytochrome c.
       0.479
ADD68928.1
PFAM: PhoP regulatory network protein YrbL; KEGG: abu:Abu_1812 hypothetical protein.
 
     0.419
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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