Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD68944.1Transcriptional regulator, Crp/Fnr family; KEGG: pca:Pcar_2562 cyclic AMP receptor protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; regulatory protein Crp. (225 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.716
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.704
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.702
ADD68328.1
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.693
ADD68943.1
KEGG: tdn:Suden_1346 putative sulfonate/nitrate transport system substrate-binding protein.
     
 0.593
ADD67924.1
KEGG: glo:Glov_1969 adenylate/guanylate cyclase with CHASE sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class- 3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
  
 
 0.589
ADD68942.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ccv:CCV52592_0423 AbcB protein.
       0.588
ADD68941.1
Putative PAS/PAC sensor protein; PFAM: PAS fold-4 domain protein; KEGG: ank:AnaeK_3310 protein of unknown function DUF438.
 
     0.566
ADD68947.1
TIGRFAM: PAS sensor protein; PFAM: ABC transporter related; Hemerythrin HHE cation binding domain protein; KEGG: dds:Ddes_1165 protein of unknown function DUF438; SMART: AAA ATPase.
     
 0.559
ADD68945.1
PFAM: Domain of unknown function DUF1858; KEGG: sun:SUN_1311 hypothetical protein.
       0.552
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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