Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD68977.1PFAM: protein of unknown function DUF342; KEGG: dde:Dde_1534 polymerase. (476 aa)    
Predicted Functional Partners:
ADD68978.1
Putative PAS/PAC sensor protein; KEGG: ppd:Ppro_1972 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: PAS fold-4 domain protein; PAS fold domain protein.
       0.773
fliW
Protein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
     0.701
ADD69051.1
KEGG: sat:SYN_00961 putative inhibitor of MCP methylation.
  
     0.678
ADD69235.1
PFAM: Flagellar protein FlgJ-like; KEGG: dal:Dalk_0989 flagellar protein FlgJ.
  
     0.638
ADD67639.1
KEGG: dal:Dalk_0295 CheC domain protein.
  
     0.621
ADD69600.1
KEGG: ccv:CCV52592_1439 flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein.
 
     0.537
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
       0.532
ADD67090.1
PFAM: MotA/TolQ/ExbB proton channel; KEGG: wsu:WS2090 motility protein A-flagellar motor component.
 
    0.516
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
 
     0.471
ADD69595.1
TIGRFAM: flagellar biosynthetic protein FlhF; PFAM: GTP-binding signal recognition particle SRP54 G- domain; KEGG: glo:Glov_3285 GTP-binding signal recognition particle SRP54 G-domain; SMART: AAA ATPase.
 
   
 0.460
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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