Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD69034.1KEGG: gsu:GSU0572 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase. (199 aa)    
Predicted Functional Partners:
ADD69033.1
PFAM: isochorismatase hydrolase; KEGG: glo:Glov_2963 isochorismatase hydrolase.
  
    0.772
ADD69031.1
PFAM: high-affinity nickel-transporter; KEGG: dde:Dde_0285 ABC-type uncharacterized transport system permease component-like; Belongs to the NiCoT transporter (TC 2.A.52) family.
       0.752
ADD69032.1
KEGG: ppd:Ppro_3679 ABC-type uncharacterized transport system periplasmic component-like protein.
       0.752
mnmA
tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.545
ADD68095.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.541
ADD69036.1
PFAM: Queuosine synthesis-like; KEGG: cco:CCC13826_1003 hypothetical protein.
       0.540
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.539
ADD68288.1
Metal-dependent hydrolase of the beta-lactamase superfamily III-like protein; KEGG: sat:SYN_01804 ribonuclease Z.
 
    0.533
ADD68634.1
KEGG: pca:Pcar_0325 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
  
   
 0.518
ADD69693.1
KEGG: tgr:Tgr7_0708 sucrose-phosphate synthase; TIGRFAM: sucrose-phosphate synthase; HAD- superfamily hydrolase, subfamily IIB; PFAM: sucrose-6F-phosphate phosphohydrolase; glycosyl transferase group 1; Haloacid dehalogenase domain protein hydrolase type 3.
   
 
 0.488
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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