STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Coexpression
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[Homology]
Score
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
ADD67712.1
KEGG: nis:NIS_0010 succinate dehydrogenase/fumarate reductase, iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin.
 
 0.987
ADD68759.1
KEGG: hypothetical protein; K00236 succinate dehydrogenase (ubiquinone) cytochrome b subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit.
  
 
 0.983
ADD68762.1
KEGG: abb:ABBFA_000761 succinate dehydrogenase iron- sulfur subunit; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
 0.982
ADD68761.1
KEGG: nme:NMB0950 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
 0.968
ADD69102.1
PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: gur:Gura_2189 pyruvate ferredoxin/flavodoxin oxidoreductase.
 
 
 0.962
ADD68346.1
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; Twin-arginine translocation pathway, signal sequence; KEGG: acp:A2cp1_3684 fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
  
 0.958
ADD68854.1
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: eca:ECA0910 putative flavoprotein subunit of a reductase.
  
 0.958
ADD68930.1
TIGRFAM: flavocytochrome c; KEGG: saz:Sama_0611 fumarate reductase flavoprotein subunit precursor; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.958
ADD69103.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: geo:Geob_2667 thiamine pyrophosphate protein domain protein TPP-binding.
  
 
 0.958
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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