Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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ADD69109.1TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: ade:Adeh_2227 isocitrate dehydrogenase, NADP- dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family. (743 aa)    
Predicted Functional Partners:
ADD68757.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: ppd:Ppro_0549 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.976
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.976
ADD68791.1
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 
 0.955
ADD69104.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: geo:Geob_2666 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.951
ADD69103.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: geo:Geob_2667 thiamine pyrophosphate protein domain protein TPP-binding.
  
 
 0.947
ADD69115.1
Aconitate hydratase 2; KEGG: gur:Gura_1939 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; TIGRFAM: aconitate hydratase 2; PFAM: Aconitase B, N-terminal; aconitate hydratase domain protein; Belongs to the aconitase/IPM isomerase family.
  
 
 0.941
ADD69102.1
PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: gur:Gura_2189 pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 
 0.939
ADD68756.1
KEGG: dol:Dole_1066 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding.
  
 
 0.933
ADD69105.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: glo:Glov_1626 4Fe-4S ferredoxin iron-sulfur binding domain protein.
    
  0.922
ADD68457.1
KEGG: pca:Pcar_0377 NifJ-like oxidoreductase, Fe-S subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain.
  
  
 0.894
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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