| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADD67644.1 | ADD69131.1 | Dacet_0864 | Dacet_2369 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: gem:GM21_2237 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.908 |
| ADD67644.1 | ADD69160.1 | Dacet_0864 | Dacet_2398 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: gme:Gmet_0870 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase. | 0.543 |
| ADD67644.1 | ahcY | Dacet_0864 | Dacet_1441 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.956 |
| ADD67644.1 | cysS | Dacet_0864 | Dacet_1781 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: gme:Gmet_0057 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.552 |
| ADD67644.1 | metE | Dacet_0864 | Dacet_1634 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.980 |
| ADD68319.1 | ADD68551.1 | Dacet_1550 | Dacet_1787 | PFAM: aminotransferase class I and II; KEGG: aeh:Mlg_2554 aminotransferase. | SMART: Rhodanese domain protein; KEGG: geo:Geob_1336 rhodanese domain-containing protein. | 0.900 |
| ADD68319.1 | ADD69131.1 | Dacet_1550 | Dacet_2369 | PFAM: aminotransferase class I and II; KEGG: aeh:Mlg_2554 aminotransferase. | KEGG: gem:GM21_2237 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.906 |
| ADD68442.1 | ADD68445.1 | Dacet_1678 | Dacet_1681 | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: wsu:WS0709 thiosulfate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: dar:Daro_3137 sulfide dehydrogenase (flavocytochrome), flavoprotein subunit. | 0.902 |
| ADD68442.1 | ADD68551.1 | Dacet_1678 | Dacet_1787 | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: wsu:WS0709 thiosulfate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | SMART: Rhodanese domain protein; KEGG: geo:Geob_1336 rhodanese domain-containing protein. | 0.904 |
| ADD68442.1 | ADD68557.1 | Dacet_1678 | Dacet_1793 | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: wsu:WS0709 thiosulfate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; Twin-arginine translocation pathway, signal sequence; KEGG: glo:Glov_1164 formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.919 |
| ADD68442.1 | ADD69131.1 | Dacet_1678 | Dacet_2369 | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: wsu:WS0709 thiosulfate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | KEGG: gem:GM21_2237 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.902 |
| ADD68445.1 | ADD68442.1 | Dacet_1681 | Dacet_1678 | PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: dar:Daro_3137 sulfide dehydrogenase (flavocytochrome), flavoprotein subunit. | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: wsu:WS0709 thiosulfate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.902 |
| ADD68445.1 | ADD68557.1 | Dacet_1681 | Dacet_1793 | PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: dar:Daro_3137 sulfide dehydrogenase (flavocytochrome), flavoprotein subunit. | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; Twin-arginine translocation pathway, signal sequence; KEGG: glo:Glov_1164 formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.902 |
| ADD68445.1 | ADD69131.1 | Dacet_1681 | Dacet_2369 | PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: dar:Daro_3137 sulfide dehydrogenase (flavocytochrome), flavoprotein subunit. | KEGG: gem:GM21_2237 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.914 |
| ADD68551.1 | ADD68319.1 | Dacet_1787 | Dacet_1550 | SMART: Rhodanese domain protein; KEGG: geo:Geob_1336 rhodanese domain-containing protein. | PFAM: aminotransferase class I and II; KEGG: aeh:Mlg_2554 aminotransferase. | 0.900 |
| ADD68551.1 | ADD68442.1 | Dacet_1787 | Dacet_1678 | SMART: Rhodanese domain protein; KEGG: geo:Geob_1336 rhodanese domain-containing protein. | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: wsu:WS0709 thiosulfate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.904 |
| ADD68551.1 | ADD68557.1 | Dacet_1787 | Dacet_1793 | SMART: Rhodanese domain protein; KEGG: geo:Geob_1336 rhodanese domain-containing protein. | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; Twin-arginine translocation pathway, signal sequence; KEGG: glo:Glov_1164 formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.910 |
| ADD68551.1 | ADD69131.1 | Dacet_1787 | Dacet_2369 | SMART: Rhodanese domain protein; KEGG: geo:Geob_1336 rhodanese domain-containing protein. | KEGG: gem:GM21_2237 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.850 |
| ADD68557.1 | ADD68442.1 | Dacet_1793 | Dacet_1678 | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; Twin-arginine translocation pathway, signal sequence; KEGG: glo:Glov_1164 formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: wsu:WS0709 thiosulfate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.919 |
| ADD68557.1 | ADD68445.1 | Dacet_1793 | Dacet_1681 | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; Twin-arginine translocation pathway, signal sequence; KEGG: glo:Glov_1164 formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: dar:Daro_3137 sulfide dehydrogenase (flavocytochrome), flavoprotein subunit. | 0.902 |
