Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADD69153.1PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; dTDP-4-dehydrorhamnose reductase; KEGG: abu:Abu_0660 NAD-dependent epimerase/dehydratase family protein. (355 aa)    
Predicted Functional Partners:
ADD69200.1
TIGRFAM: nucleotide sugar dehydrogenase; KEGG: nis:NIS_0741 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase.
 0.952
ADD69201.1
PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: hhe:HH0647 nucleotide sugar dehydratase.
     
 
0.900
rpsC
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
  0.827
rpsS
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.824
rpsZ
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
   
  0.821
ADD68603.1
KEGG: gsu:GSU0859 UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase.
    
 0.819
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.817
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 0.816
ADD69693.1
KEGG: tgr:Tgr7_0708 sucrose-phosphate synthase; TIGRFAM: sucrose-phosphate synthase; HAD- superfamily hydrolase, subfamily IIB; PFAM: sucrose-6F-phosphate phosphohydrolase; glycosyl transferase group 1; Haloacid dehalogenase domain protein hydrolase type 3.
  
 
 0.813
ADD69694.1
Sucrose synthase; Catalyzes the reversible conversion of sucrose and a nucleotide disphosphate (NDP) into fructose and NDP-glucose; although the reaction is freely reversible in vitro, the physiological reaction seems to be sucrose cleavage. Unlike characterized plant enzymes prefers ADP as a cosubstrate, whereas plants prefer UDP (By similarity). Its preference for ADP over UDP suggests it may directly link sucrose and glycogen metabolism (Probable). Belongs to the glycosyltransferase 1 family.
  
 
 0.809
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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