Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD69206.1KEGG: dvm:DvMF_3086 DNA repair protein RadC; TIGRFAM: DNA repair protein RadC; PFAM: DNA repair protein RadC; Belongs to the UPF0758 family. (221 aa)    
Predicted Functional Partners:
ADD67964.1
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
  
 0.894
ADD68037.1
KEGG: gbm:Gbem_2462 rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC.
  
  
 0.839
ADD69207.1
PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; dTDP-4- dehydrorhamnose reductase; KEGG: gsu:GSU0385 NADH dehydrogenase subunit, putative.
       0.758
ADD67627.1
KEGG: oan:Oant_3669 DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein.
  
  
 0.712
ADD69669.1
KEGG: mca:MCA1124 competence protein F.
 
    0.690
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.626
ADD69208.1
PFAM: Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thioredoxin domain; KEGG: dds:Ddes_1441 redoxin domain protein.
  
    0.625
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.624
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
 
   
 0.589
ADD68500.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; KEGG: pin:Ping_1203 sensor histidine kinase PAS domain-containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein.
  
    0.562
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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