Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD69262.1TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; CHASE4 domain protein; histidine kinase HAMP region domain protein; KEGG: hch:HCH_02106 response regulator; SMART: GGDEF domain containing protein. (516 aa)    
Predicted Functional Partners:
ADD67940.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; KEGG: gme:Gmet_1707 PAS/PAC sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.972
ADD68500.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; KEGG: pin:Ping_1203 sensor histidine kinase PAS domain-containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein.
 
 
 0.967
ADD68190.1
Multi-sensor hybrid histidine kinase; KEGG: vcj:VCD_002990 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein.
 
 
 0.952
ADD67941.1
KEGG: dar:Daro_2902 response regulator receiver; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver.
  
 0.948
ADD68495.1
Integral membrane sensor hybrid histidine kinase; KEGG: sse:Ssed_2865 signal transduction histidine kinase-like protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein.
 
 0.947
ADD68821.1
Multi-sensor hybrid histidine kinase; KEGG: swp:swp_2315 PAS domain protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein.
 
 
 0.883
ADD69090.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: wsu:WS0108 GGDEF family protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
 0.883
ADD68774.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; Cache type 2 domain protein; PAS fold domain protein; KEGG: tdn:Suden_1941 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein.
 
 
 0.882
ADD67689.1
KEGG: rfr:Rfer_0891 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
  
 0.879
ADD66950.1
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; KEGG: wsu:WS0415 sensor kinase of two-component regulatory system; SMART: ATP-binding region ATPase domain protein; GAF domain protein; PAS domain containing protein.
 
 
 0.876
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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