Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD69308.1KEGG: dps:DP0159 cytochrome-c3 hydrogenase (NiFeSe), large subunit; PFAM: nickel-dependent hydrogenase large subunit. (479 aa)    
Predicted Functional Partners:
ADD69307.1
KEGG: dps:DP0160 periplasmic [NiFeSe] hydrogenase, small subunit [precursor]; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit.
 
 0.999
ADD67995.1
TIGRFAM: hydrogenase (NiFe) small subunit HydA; KEGG: glo:Glov_0144 hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit.
 
 0.996
ADD69245.1
TIGRFAM: hydrogenase (NiFe) small subunit HydA; KEGG: gme:Gmet_3332 Ni-Fe hydrogenase, small subunit:twin-arginine translocation pathway signal; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit.
 
 0.996
ADD67984.1
KEGG: gur:Gura_0874 Ni/Fe-hydrogenase, b-type cytochrome subunit; TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561.
 
 
 0.936
ADD69246.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: gsu:GSU0122 nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
  
 
0.919
ADD67992.1
KEGG: gur:Gura_1946 nickel-dependent hydrogenase, large subunit; PFAM: nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
  
 
0.918
ADD69247.1
KEGG: gme:Gmet_3329 peptidase M52, hydrogenase maturation peptidase; TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein.
 
  
 0.852
ADD67991.1
KEGG: gur:Gura_1947 hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein.
 
  
 0.850
ADD67220.1
PFAM: hydrogenase formation HypD protein; KEGG: dps:DP0579 hydrogenase accessory protein HypD.
 
 
 0.819
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.815
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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