STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adeTIGRFAM: adenine deaminase; KEGG: sun:SUN_0856 adenine deaminase; PFAM: amidohydrolase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (526 aa)    
Predicted Functional Partners:
ADD68067.1
TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.914
ADD69361.1
PFAM: Xanthine/uracil/vitamin C permease; KEGG: lhk:LHK_00455 probable membrane permease protein.
     
 0.808
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.563
ADD69362.1
PFAM: protein of unknown function DUF454; KEGG: mmw:Mmwyl1_1530 hypothetical protein.
       0.518
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.485
ADD69363.1
PFAM: SNARE associated Golgi protein; phospholipase D/Transphosphatidylase; KEGG: noc:Noc_1912 phospholipase D/transphosphatidylase; SMART: phospholipase D/Transphosphatidylase.
  
    0.435
ADD69364.1
PFAM: Endonuclease/exonuclease/phosphatase; KEGG: reu:Reut_A3204 endonuclease/exonuclease/phosphatase.
       0.426
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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