Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD69460.1Protein serine/threonine phosphatase; KEGG: pub:SAR11_0064 sigma factor SigB regulation protein; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. (520 aa)    
Predicted Functional Partners:
ADD67983.1
KEGG: noc:Noc_2976 anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.891
ADD69608.1
Anti-sigma-factor antagonist; KEGG: pca:Pcar_1874 anti-anti-sigma regulatory factor; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.874
ADD68669.1
Anti-sigma-factor antagonist; KEGG: pca:Pcar_1874 anti-anti-sigma regulatory factor; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.869
ADD67653.1
Putative anti-sigma regulatory factor, serine/threonine protein kinase; KEGG: cvi:CV_0472 two-component response regulator.
 
 
 0.859
ADD69459.1
TIGRFAM: metal dependent phophohydrolase; PFAM: Metal-dependent hydrolase HDOD; metal- dependent phosphohydrolase HD sub domain; KEGG: mms:mma_0564 signal transduction protein; SMART: metal-dependent phosphohydrolase HD region.
 
     0.858
ADD69458.1
Response regulator receiver protein; KEGG: dal:Dalk_1576 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; SMART: response regulator receiver.
  
  
 0.820
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
       0.812
ADD67940.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; KEGG: gme:Gmet_1707 PAS/PAC sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
  
 0.808
ADD69609.1
KEGG: geo:Geob_2165 PBS lyase heat domain protein repeat-containing protein; PFAM: PBS lyase HEAT domain protein repeat- containing protein; SMART: PBS lyase HEAT domain protein repeat- containing protein.
 
 
 0.801
ADD68500.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; KEGG: pin:Ping_1203 sensor histidine kinase PAS domain-containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein.
  
  
 0.794
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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