STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADD69493.1TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: pca:Pcar_1453 O-acetylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein. (426 aa)    
Predicted Functional Partners:
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 0.994
ADD67644.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.956
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.922
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.912
ADD69278.1
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: gsu:GSU1183 O-acetyl-L-homoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein.
  
  
 
0.904
ADD68189.1
KEGG: gme:Gmet_1629 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding.
  
 
 0.859
ADD69131.1
KEGG: gem:GM21_2237 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.854
ADD69020.1
KEGG: gsu:GSU0486 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit.
   
 
  0.810
ADD68170.1
KEGG: gur:Gura_2810 S-isoprenylcysteine methyltransferase-like protein.
     
  0.800
ADD69491.1
PFAM: Methyltransferase type 11; KEGG: pca:Pcar_1066 putative methyltransferase.
     
 0.782
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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