| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADD66863.1 | ADD68067.1 | Dacet_0057 | Dacet_1295 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.906 |
| ADD66863.1 | ADD68152.1 | Dacet_0057 | Dacet_1382 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: dat:HRM2_09650 UshA; Belongs to the 5'-nucleotidase family. | 0.904 |
| ADD66863.1 | ADD68913.1 | Dacet_0057 | Dacet_2151 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: phosphoribosyltransferase; KEGG: avn:Avin_47930 xanthine phosphoribosyltransferase. | 0.938 |
| ADD66863.1 | ADD69325.1 | Dacet_0057 | Dacet_2566 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 5'-nucleotidase; KEGG: dps:DP1354 5'-nucleotidase; PFAM: 5-nucleotidase. | 0.900 |
| ADD66863.1 | ADD69569.1 | Dacet_0057 | Dacet_2818 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: glutamine amidotransferase class-I; KEGG: aav:Aave_0325 glutamine amidotransferase class-I. | 0.907 |
| ADD66863.1 | guaA | Dacet_0057 | Dacet_0079 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.963 |
| ADD66863.1 | guaB | Dacet_0057 | Dacet_0078 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.938 |
| ADD66863.1 | surE | Dacet_0057 | Dacet_1099 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.901 |
| ADD68067.1 | ADD66863.1 | Dacet_1295 | Dacet_0057 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.906 |
| ADD68067.1 | ADD68152.1 | Dacet_1295 | Dacet_1382 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: dat:HRM2_09650 UshA; Belongs to the 5'-nucleotidase family. | 0.913 |
| ADD68067.1 | ADD68913.1 | Dacet_1295 | Dacet_2151 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | PFAM: phosphoribosyltransferase; KEGG: avn:Avin_47930 xanthine phosphoribosyltransferase. | 0.958 |
| ADD68067.1 | ADD68975.1 | Dacet_1295 | Dacet_2213 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | KEGG: gbm:Gbem_3337 MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase. | 0.916 |
| ADD68067.1 | ADD69325.1 | Dacet_1295 | Dacet_2566 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 5'-nucleotidase; KEGG: dps:DP1354 5'-nucleotidase; PFAM: 5-nucleotidase. | 0.900 |
| ADD68067.1 | ADD69569.1 | Dacet_1295 | Dacet_2818 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | PFAM: glutamine amidotransferase class-I; KEGG: aav:Aave_0325 glutamine amidotransferase class-I. | 0.920 |
| ADD68067.1 | gmk | Dacet_1295 | Dacet_1560 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.945 |
| ADD68067.1 | guaA | Dacet_1295 | Dacet_0079 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.956 |
| ADD68067.1 | guaB | Dacet_1295 | Dacet_0078 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.954 |
| ADD68067.1 | surE | Dacet_1295 | Dacet_1099 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
| ADD68152.1 | ADD66863.1 | Dacet_1382 | Dacet_0057 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: dat:HRM2_09650 UshA; Belongs to the 5'-nucleotidase family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.904 |
| ADD68152.1 | ADD68067.1 | Dacet_1382 | Dacet_1295 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: dat:HRM2_09650 UshA; Belongs to the 5'-nucleotidase family. | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ank:AnaeK_0134 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.913 |
