STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADD69579.1PFAM: Silent information regulator protein Sir2; KEGG: sat:SYN_01020 Sir2 family NAD-dependent deacetylase. (253 aa)    
Predicted Functional Partners:
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.921
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.915
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.914
ADD68975.1
KEGG: gbm:Gbem_3337 MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase.
    
  0.901
ADD69580.1
PFAM: histidine triad (HIT) protein; KEGG: dde:Dde_1973 HIT family protein.
    
  0.831
ADD69581.1
KEGG: sat:SYN_02932 hypothetical protein.
       0.791
ADD69582.1
N-acetylglucosaminyl transferase-like protein; KEGG: vsa:VSAL_I2224 tetratricopeptide repeat protein.
       0.791
ADD67493.1
PFAM: NERD domain protein; KEGG: shn:Shewana3_0647 NERD domain-containing protein.
  
 
 0.761
ADD67380.1
KEGG: see:SNSL254_A4376 hypothetical protein.
   
   0.729
ADD68237.1
KEGG: dal:Dalk_1289 hypothetical protein.
   
   0.729
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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