Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ADD69590.1KEGG: scl:sce7931 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein. (389 aa)    
Predicted Functional Partners:
ADD69458.1
Response regulator receiver protein; KEGG: dal:Dalk_1576 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 0.848
ADD69471.1
KEGG: lip:LI1142 CheY-like receiver; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 0.845
uvrA
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.823
mqnC
Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.816
ADD69587.1
N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: dde:Dde_1370 N-acetylmuramoyl-L-alanine amidase; SMART: cell wall hydrolase/autolysin.
       0.813
ADD67789.1
Two component transcriptional regulator, winged helix family; KEGG: spe:Spro_1508 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
 
 
 0.812
ADD68001.1
Two component transcriptional regulator, winged helix family; KEGG: dps:DP1885 PHO two-component system sensor histidine kinase; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
 
 
 0.812
ADD68819.1
Two component transcriptional regulator, winged helix family; KEGG: pat:Patl_0225 osmolarity response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
 
 
 0.798
ADD69123.1
KEGG: gsu:GSU0598 sigma-54 dependent DNA-binding response regulator; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 
 0.778
ADD69589.1
PFAM: protein of unknown function DUF342; KEGG: dde:Dde_1534 polymerase.
       0.777
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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