Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADD69629.1Diguanylate phosphodiesterase; KEGG: gsu:GSU1149 EAL domain-containing protein; PFAM: EAL domain protein; Metal-dependent hydrolase HDOD; SMART: EAL domain protein. (411 aa)    
Predicted Functional Partners:
ADD66927.1
Diguanylate cyclase/phosphodiesterase with extracellular sensor; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; KEGG: ccv:CCV52592_0162 endonuclease IV; SMART: EAL domain protein; GGDEF domain containing protein.
 
   
 0.611
ADD68497.1
Diguanylate phosphodiesterase; KEGG: wsu:WS0772 sensor protein; PFAM: EAL domain protein; SMART: EAL domain protein.
  
   
 0.568
ADD68793.1
Diguanylate cyclase/phosphodiesterase; KEGG: abu:Abu_0086 EAL/GGDEF domain-containing protein; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
   
 0.519
ADD68500.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; KEGG: pin:Ping_1203 sensor histidine kinase PAS domain-containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein.
 
   
 0.502
ADD68774.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; Cache type 2 domain protein; PAS fold domain protein; KEGG: tdn:Suden_1941 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein.
 
   
 0.494
ADD69630.1
KEGG: gme:Gmet_3027 IclR family transcriptional regulator; PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR.
       0.452
ADD69085.1
KEGG: vpa:VPA0746 chemotaxis protein CheV; PFAM: CheW domain protein; response regulator receiver; SMART: response regulator receiver; CheW domain protein.
 
     0.451
ADD69628.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dol:Dole_2297 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
       0.426
ADD69090.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: wsu:WS0108 GGDEF family protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
   
 0.417
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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