Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ADD69641.1PFAM: Silent information regulator protein Sir2; KEGG: nis:NIS_0515 Sir2 family transcriptional regulator. (274 aa)    
Predicted Functional Partners:
ADD67493.1
PFAM: NERD domain protein; KEGG: shn:Shewana3_0647 NERD domain-containing protein.
  
 
 0.761
ADD67380.1
KEGG: see:SNSL254_A4376 hypothetical protein.
   
   0.729
ADD68237.1
KEGG: dal:Dalk_1289 hypothetical protein.
   
   0.729
ADD68746.1
KEGG: dal:Dalk_1289 hypothetical protein.
   
   0.729
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.681
ADD67930.1
KEGG: gem:GM21_2320 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein.
  
    0.555
ADD68276.1
Transcriptional regulator, XRE family; KEGG: aha:AHA_0244 DNA-binding protein; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
  
    0.555
ADD68940.1
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: gur:Gura_2800 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.551
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.530
ADD68775.1
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: abu:Abu_1136 hypothetical protein.
  
    0.518
Your Current Organism:
Denitrovibrio acetiphilus
NCBI taxonomy Id: 522772
Other names: D. acetiphilus DSM 12809, Denitrovibrio acetiphilus DSM 12809, Denitrovibrio acetiphilus N2460, Denitrovibrio acetiphilus str. DSM 12809, Denitrovibrio acetiphilus strain DSM 12809
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